Associated Papers
APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus.
Chen Z et al.
Journal of Virology, 2025
Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s.
Hou S et al.
The Journal of Biological Chemistry, 2021
APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (-)-DNA.
Chen Z et al.
The Journal of Biological Chemistry, 2021
Highly-potent, synthetic APOBEC3s restrict HIV-1 through deamination-independent mechanisms.
McDonnell MM et al.
Plos Pathogens, 2021
Targeting natural splicing plasticity of APOBEC3B restricts its expression and mutagenic activity.
Rouf Banday A et al.
Communications Biology, 2021
Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B.
Shi K et al.
Faseb Bioadvances, 2020
Understanding the structural details of APOBEC3-DNA interactions using graph-based representations.
Ng JC et al.
Current Research in Structural Biology, 2020
The DNA deaminase APOBEC3B interacts with the cell-cycle protein CDK4 and disrupts CDK4-mediated nuclear import of Cyclin D1.
McCann JL et al.
The Journal of Biological Chemistry, 2019
Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation.
Matsumoto T et al.
Scientific Reports, 2019
Determinants of Oligonucleotide Selectivity of APOBEC3B.
Wagner JR et al.
Journal of Chemical Information and Modeling, 2019
Structural Analysis of the Active Site and DNA Binding of Human Cytidine Deaminase APOBEC3B.
Hou S et al.
Journal of Chemical Theory and Computation, 2019
APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces.
Salamango DJ et al.
Journal of Molecular Biology, 2018
Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Xiao X et al.
Nucleic Acids Research, 2017
Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.
Shi K et al.
Nature Structural & Molecular Biology, 2017
Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.
Byeon IJ et al.
Biochemistry, 2016
Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities.
Mitra M et al.
Retrovirology, 2015
Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits.
Hassan MA et al.
Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology, 2014
Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA.
Caval V et al.
Molecular Biology and Evolution, 2014
APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages.
Chaipan C et al.
Journal of Virology, 2013