Varaico: Literature-Extracted Genetic Variants

Gene:SGK1
Variant:p.C86S
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SGK1

NM_001143676.3:p.C86S

Associated Papers

Impact of Deleterious Mutations on Structure, Function and Stability of Serum/Glucocorticoid Regulated Kinase 1: A Gene to Diseases Correlation.

AlAjmi MF et al.

Frontiers in Molecular Biosciences, 2021

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.

Sommer EM et al.

The Biochemical Journal, 2013

23581296 (PubMed )
Supplement: bj4520499add.pdf

Hsp90 regulates the phosphorylation and activity of serum- and glucocorticoid-regulated kinase-1.

Belova L et al.

The Journal of Biological Chemistry, 2008

mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation.

Hong F et al.

Molecular Cell, 2008

A novel N-terminal hydrophobic motif mediates constitutive degradation of serum- and glucocorticoid-induced kinase-1 by the ubiquitin-proteasome pathway.

Bogusz AM et al.

The Febs Journal, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."