Varaico: Literature-Extracted Genetic Variants

Gene:SGO1
Variant:p.N61I
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SGO1

NM_001199251.3:p.N61I

Associated Papers

A positive feedback mechanism ensures proper assembly of the functional inner centromere during mitosis in human cells.

Liang C et al.

The Journal of Biological Chemistry, 2019

An Alternatively Spliced Bifunctional Localization Signal Reprograms Human Shugoshin 1 to Protect Centrosomal Instead of Centromeric Cohesin.

Mohr L et al.

Cell Reports, 2015

SGO1C is a non-functional isoform of Shugoshin and can disrupt sister chromatid cohesion by interacting with PP2A-B56.

Wong WK et al.

Cell Cycle (georgetown, Tex.), 2015

A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.

Kahyo T et al.

Oncogene, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."