Associated Papers
Targeted Next-Generation Sequencing of the Leptin-Melanocortin Pathway in Severe Obesity.
Faccioli N et al.
Obesity (silver Spring, Md.), 2026
Sequencing methods, functional characterization, prevalence, and penetrance of rare coding mutations in panels of monogenic obesity genes from the leptin-melanocortin pathway: A systematic review.
Dosda S et al.
Obesity Reviews : an Official Journal of the International Association for the Study of Obesity, 2024
The Tip of the Iceberg: Genotype of Puerto Rican Pediatric Obesity.
Melendez-Montañez JM et al.
Genes, 2024
SIGMA leverages protein structural information to predict the pathogenicity of missense variants.
Zhao H et al.
Cell Reports Methods, 2024
Role of the Beta and Gamma Isoforms of the Adapter Protein SH2B1 in Regulating Energy Balance.
Argetsinger LS et al.
Endocrinology, 2023
SH2B1 variants as potential causes of non-syndromic monogenic obesity in a Brazilian cohort.
da Fonseca ACP et al.
Eating and Weight Disorders : Ewd, 2022
Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.
Jiang L et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2018
High Prevalence of Rare Monogenic Forms of Obesity in Obese Guadeloupean Afro-Caribbean Children.
Foucan L et al.
The Journal of Clinical Endocrinology and Metabolism, 2018
The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.
Giuranna J et al.
Obesity Facts, 2018
Growth hormone signaling pathways.
Carter-Su C et al.
Growth Hormone & Igf Research : Official Journal of the Growth Hormone Research Society and the International Igf Research Society, 2016
Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1.
Pearce LR et al.
Endocrinology, 2014
Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
Doche ME et al.
The Journal of Clinical Investigation, 2012