Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.E208*
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SH2B3

NM_005475.3:p.E208*

Associated Papers

SH2B3 (Lnk) Mutations in Myeloid Neoplasms: Morphologic Spectrum, Co-Mutation Patterns, and Clinical Correlates.

Tefferi A et al.

American Journal of Hematology, 2025

Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Gao F et al.

Cancer Medicine, 2023

36971051 (PubMed )
Supplement: CAM4-12-10267-s001.xlsx › Sheet1

PAX6 disease models for aniridia.

Abdolkarimi D et al.

Indian Journal of Ophthalmology, 2022

Actionable Molecular Alterations Are Revealed in Majority of Advanced Non-Small Cell Lung Cancer Patients by Genomic Tumor Profiling at Progression after First Line Treatment.

Frank MS et al.

Cancers, 2021

35008297 (PubMed )
Supplement: cancers-14-00132-s001.zip › Supplementary_Table_S1.xlsx › Overview_ver2

Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.

Gao F et al.

Frontiers in Genetics, 2021

34925435 (PubMed )
Supplement: DataSheet2.xlsx › Sheet1

The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders.

Maslah N et al.

Leukemia, 2017

LNK mutations and myeloproliferative disorders.

McMullin MF et al.

American Journal of Hematology, 2016

12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?

Auburger G et al.

World Journal of Diabetes, 2014

Role of the adaptor protein LNK in normal and malignant hematopoiesis.

Gery S et al.

Oncogene, 2013

LNK can also be mutated outside PH and SH2 domains in myeloproliferative neoplasms with and without V617FJAK2 mutation.

Hurtado C et al.

Leukemia Research, 2011

[Classification for myeloproliferative neoplasms and function of novel mutations].

Kirito K

[rinsho Ketsueki] the Japanese Journal of Clinical Hematology, 2011

When the Brakes are Lost: LNK Dysfunction in Mice, Men, and Myeloproliferative Neoplasms.

Oh ST

Therapeutic Advances in Hematology, 2011

LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations.

Pardanani A et al.

Leukemia, 2010

LNK mutations in JAK2 mutation-negative erythrocytosis.

Lasho TL et al.

The New England Journal of Medicine, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."