Varaico: Literature-Extracted Genetic Variants

Gene:SH2B3
Variant:p.G220R
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SH2B3

NM_005475.3:p.G220R

Associated Papers

Diagnostic relevance of SH2B3 mutations in suspected myeloid malignancies and acute leukemia: insights from a large-scale NGS-based screening study.

Ben Dhia L et al.

Blood Cancer Journal, 2025

41136376 (PubMed )
Supplement: 41408_2025_1392_MOESM2_ESM.pdf

Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing.

Newman S et al.

Cancer Discovery, 2021

34301788 (PubMed )
Supplement: cd-20-1631_supplementary_tables_suppst1.xlsx › S2.Somatic_Findings_Summary

Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes.

Takahashi K et al.

Nature Communications, 2018

29991687 (PubMed )
Supplement: 41467_2018_4924_MOESM1_ESM.pdf

The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders.

Maslah N et al.

Leukemia, 2017

LNK mutations and myeloproliferative disorders.

McMullin MF et al.

American Journal of Hematology, 2016

Role of the adaptor protein LNK in normal and malignant hematopoiesis.

Gery S et al.

Oncogene, 2013

The Lnk adaptor protein: a key regulator of normal and pathological hematopoiesis.

Velazquez L

Archivum Immunologiae Et Therapiae Experimentalis, 2012

[Classification for myeloproliferative neoplasms and function of novel mutations].

Kirito K

[rinsho Ketsueki] the Japanese Journal of Clinical Hematology, 2011

LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations.

Pardanani A et al.

Leukemia, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."