Associated Papers
SHBG Gene Polymorphisms and Their Influence on Serum SHBG, Total and Free Testosterone Concentrations in Men.
Walravens J et al.
The Journal of Clinical Endocrinology and Metabolism, 2025
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction.
Lunghi B et al.
International Journal of Molecular Sciences, 2023
XAF1 as a modifier of p53 function and cancer susceptibility.
Pinto EM et al.
Science Advances, 2020
Steroid hormone-related polymorphisms associate with the development of bone erosions in rheumatoid arthritis and help to predict disease progression: Results from the REPAIR consortium.
Sánchez-Maldonado JM et al.
Scientific Reports, 2019
Genetic polymorphisms of the SHBG gene can be the effect on SHBG and HDL-cholesterol levels in Coronary Heart Disease: a case-control study.
Kurnaz-Gomleksiz O et al.
Molecular Biology Reports, 2019
Genetic Polymorphism in Sex Hormone-binding Globulin With a Prognosis of Androgen Deprivation Therapy in Metastatic Prostate Cancer Among Japanese Men.
Shiota M et al.
Clinical Genitourinary Cancer, 2019
Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients.
Canet LM et al.
The Pharmacogenomics Journal, 2019
Loss and gain of N-linked glycosylation sequons due to single-nucleotide variation in cancer.
Fan Y et al.
Scientific Reports, 2018
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
Lonjou C et al.
Bmc Cancer, 2017
An independent validation study of three single nucleotide polymorphisms at the sex hormone-binding globulin locus for testosterone levels identified by genome-wide association studies.
Sato Y et al.
Human Reproduction Open, 2017
The association between sex hormone-binding globulin gene polymorphism with bone mineral density.
Zha XY et al.
Steroids, 2016
Common Variants in the Sex Hormone-Binding Globulin (SHBG) Gene Influence SHBG Levels in Women with Polycystic Ovary Syndrome.
Abu-Hijleh TM et al.
Annals of Nutrition & Metabolism, 2016
Study of Sex Hormone-binding Globulin Gene Polymorphism and Risk of Type 2 Diabetes Mellitus in Egyptian Men.
El Tarhouny SA et al.
The West Indian Medical Journal, 2015
Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.
Karageorgos I et al.
Human Genomics, 2015
Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.
Witkiewicz AK et al.
Nature Communications, 2015
A steroid metabolizing gene variant in a polyfactorial model improves risk prediction in a high incidence breast cancer population.
Jupe ER et al.
Bba Clinical, 2014
Genetic polymorphisms potentially associated with response to metformin in postmenopausal diabetics suffering and not suffering with cancer.
Berstein LM et al.
Cell Cycle (georgetown, Tex.), 2013
Associations between polymorphisms in sex steroid related genes and autistic-like traits.
Zettergren A et al.
Psychoneuroendocrinology, 2013
Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
Jin G et al.
Human Molecular Genetics, 2012
Sex hormone-binding globulin levels are not causally related to venous thrombosis risk in women not using hormonal contraceptives.
Stegeman BH et al.
Journal of Thrombosis and Haemostasis : Jth, 2012
Genome-wide association study of circulating estradiol, testosterone, and sex hormone-binding globulin in postmenopausal women.
Prescott J et al.
Plos One, 2012
Estrogen metabolism genotypes, use of long-term hormone replacement therapy and risk of postmenopausal breast cancer.
Cerne JZ et al.
Oncology Reports, 2011
Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes.
Rudolph A et al.
Endocrine-related Cancer, 2011
Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.
Zhang B et al.
The Lancet. Oncology, 2011
Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk.
Sainz J et al.
Endocrine-related Cancer, 2011
Sex hormone-binding globulin genetic variation: associations with type 2 diabetes mellitus and polycystic ovary syndrome.
Chen C et al.
Minerva Endocrinologica, 2010
Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men.
Huhtaniemi IT et al.
The Journal of Clinical Endocrinology and Metabolism, 2010
Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.
Perry JR et al.
Human Molecular Genetics, 2010
Effects of polymorphisms of the sex hormone-binding globulin (SHBG) gene on free estradiol and bone mineral density.
Napoli N et al.
Bone, 2009
Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists.
Sigurdson AJ et al.
Breast Cancer Research and Treatment, 2009
Sex hormone-binding globulin and risk of type 2 diabetes in women and men.
Ding EL et al.
The New England Journal of Medicine, 2009
Variants in hormone-related genes and the risk of biliary tract cancers and stones: a population-based study in China.
Park SK et al.
Carcinogenesis, 2009
Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.
Freedman ND et al.
Carcinogenesis, 2009
Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.
Thompson DJ et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008
Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.
Diergaarde B et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008
A genome-wide association study identifies protein quantitative trait loci (pQTLs).
Melzer D et al.
Plos Genetics, 2008
Associations of serum sex hormone binding globulin (SHBG) levels with SHBG gene polymorphisms in the CARDIA Male Hormone Study.
Turk A et al.
American Journal of Epidemiology, 2008
Evaluation of genetic variations in the androgen and estrogen metabolic pathways as risk factors for sporadic and familial prostate cancer.
Cunningham JM et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007
Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants.
Low YL et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007
Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study.
Garcia-Closas M et al.
Bmc Cancer, 2007
Variant in sex hormone-binding globulin gene and the risk of prostate cancer.
Berndt SI et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2007
Implications of gene-environment interaction in studies of gene variants in breast cancer: an example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene.
Low YL et al.
Cancer Research, 2006
Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women.
Warren R et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2006
Phytoestrogen exposure, polymorphisms in COMT, CYP19, ESR1, and SHBG genes, and their associations with prostate cancer risk.
Low YL et al.
Nutrition and Cancer, 2006
Polymorphisms associated with circulating sex hormone levels in postmenopausal women.
Dunning AM et al.
Journal of the National Cancer Institute, 2004
Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition.
Rebbeck TR et al.
Menopause (new York, N.y.), 0