Varaico: Literature-Extracted Genetic Variants

Gene:SHC1
Variant:p.A376S
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SHC1

NM_001130040.2:p.A376S

Associated Papers

Effects of HIV-1 reverse transcriptase connection subdomain mutations on polypurine tract removal and initiation of (+)-strand DNA synthesis.

Betancor G et al.

Nucleic Acids Research, 2015

Connection subdomain mutations in HIV-1 subtype-C treatment-experienced patients enhance NRTI and NNRTI drug resistance.

Delviks-Frankenberry KA et al.

Virology, 2013

Connection domain mutations in HIV-1 reverse transcriptase do not impact etravirine susceptibility and virologic responses to etravirine-containing regimens.

Gupta S et al.

Antimicrobial Agents and Chemotherapy, 2011

HIV-1 reverse transcriptase connection domain mutations: dynamics of emergence and implications for success of combination antiretroviral therapy.

von Wyl V et al.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 2010

Clinical relevance of substitutions in the connection subdomain and RNase H domain of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naïve patients.

Hachiya A et al.

Antiviral Research, 2009

Variations in reverse transcriptase and RNase H domain mutations in human immunodeficiency virus type 1 clinical isolates are associated with divergent phenotypic resistance to zidovudine.

Ntemgwa M et al.

Antimicrobial Agents and Chemotherapy, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."