Varaico: Literature-Extracted Genetic Variants

Gene:SHC1
Variant:p.M230I
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SHC1

NM_001130040.2:p.M230I

Associated Papers

Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs.

Boyer PL et al.

Journal of Virology, 2019

K65R and K65A substitutions in HIV-1 reverse transcriptase enhance polymerase fidelity by decreasing both dNTP misinsertion and mispaired primer extension efficiencies.

Garforth SJ et al.

Journal of Molecular Biology, 2010

Retroviral mutation rates and reverse transcriptase fidelity.

Svarovskaia ES et al.

Frontiers in Bioscience : a Journal and Virtual Library, 2003

A mutation in the primer grip region of HIV-1 reverse transcriptase that confers reduced fidelity of DNA synthesis.

Gutiérrez-Rivas M et al.

Nucleic Acids Research, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."