Associated Papers
Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex.
Huang P et al.
Developmental Cell, 2022
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex.
Qi X et al.
Science (new York, N.y.), 2018
The mutational spectrum of holoprosencephaly-associated changes within the SHH gene in humans predicts loss-of-function through either key structural alterations of the ligand or its altered synthesis.
Roessler E et al.
Human Mutation, 2009
A sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1.
Martinelli DC et al.
The Journal of Biological Chemistry, 2009
Holoprosencephaly: clinical, anatomic, and molecular dimensions.
Cohen MM
Birth Defects Research. Part A, Clinical and Molecular Teratology, 2006
Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly.
Maity T et al.
Proceedings of the National Academy of Sciences of the United States of America, 2005
Functional characterization of sonic hedgehog mutations associated with holoprosencephaly.
Traiffort E et al.
The Journal of Biological Chemistry, 2004
Select a paper to view details