Varaico: Literature-Extracted Genetic Variants

Gene:SHLD3
Variant:p.P58A
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SHLD3

NM_001365341.2:p.P58A

Associated Papers

Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair.

Dai Y et al.

The Journal of Biological Chemistry, 2020

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.

Ghezraoui H et al.

Nature, 2018

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

Gupta R et al.

Cell, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."