Associated Papers
Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Katinas JM et al.
Biochemistry, 2024
The loss of SHMT2 mediates 5-fluorouracil chemoresistance in colorectal cancer by upregulating autophagy.
Chen J et al.
Oncogene, 2021
Mitochondrial translation requires folate-dependent tRNA methylation.
Morscher RJ et al.
Nature, 2018
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