Varaico: Literature-Extracted Genetic Variants

Gene:SIK1
Variant:p.K56R
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SIK1

NM_173354.5:p.K56R

Associated Papers

The protein kinase SIK downregulates the polarity protein Par3.

Vanlandewijck M et al.

Oncotarget, 2018

Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase.

Lönn P et al.

The Journal of Biological Chemistry, 2012

TGFbeta induces SIK to negatively regulate type I receptor kinase signaling.

Kowanetz M et al.

The Journal of Cell Biology, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."