Varaico: Literature-Extracted Genetic Variants

Gene:SIK2
Variant:p.T175A
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SIK2

NM_015191.3:p.T175A

Associated Papers

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses.

Hutchinson LD et al.

Cell Death & Disease, 2020

The KLDpT activation loop motif is critical for MARK kinase activity.

Sonntag T et al.

Plos One, 2019

14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).

Sonntag T et al.

The Febs Journal, 2018

SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.

Henriksson E et al.

Journal of Cell Science, 2015

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.

Patel K et al.

Nature Communications, 2014

25088745 (PubMed )
Supplement: ncomms5535-s1.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."