Associated Papers
Salt-inducible Kinase Regulation of Adipose Tissue Metabolism.
Shi F et al.
Endocrinology, 2025
The SIK3-N783Y mutation is associated with the human natural short sleep trait.
Chen H et al.
Proceedings of the National Academy of Sciences of the United States of America, 2025
The KLDpT activation loop motif is critical for MARK kinase activity.
Sonntag T et al.
Plos One, 2019
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.
Patra KC et al.
Nature Cell Biology, 2018
14-3-3 proteins mediate inhibitory effects of cAMP on salt-inducible kinases (SIKs).
Sonntag T et al.
The Febs Journal, 2018
Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.
Sonntag T et al.
Plos One, 2017
SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes.
Henriksson E et al.
Journal of Cell Science, 2015
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver.
Patel K et al.
Nature Communications, 2014
25088745 (PubMed )
Supplement: ncomms5535-s1.pdf
Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.
Sakamaki J et al.
Nature Cell Biology, 2014
The tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases.
Walkinshaw DR et al.
The Journal of Biological Chemistry, 2013
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