Associated Papers
LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity.
Yan P et al.
Cell Reports, 2021
Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Dai H et al.
Nature Communications, 2015
The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression.
Miranda MX et al.
European Heart Journal, 2015
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