Varaico: Literature-Extracted Genetic Variants

Gene:SIRT6
Variant:p.N308K
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SIRT6

NM_016539.4:p.N308K

Associated Papers

A study on the correlation between SIRT6 gene polymorphisms and glioma risk in Chinese Han Population.

Gu L et al.

The International Journal of Neuroscience, 2025

Factors involved in human healthy aging: insights from longevity individuals.

Yin FQ et al.

Frontiers of Medicine, 2025

Structural Insights Into centSIRT6: Bioinformatic Analysis of N308K and A313S Substitution Effects.

Lagunas-Rangel FA

Bioinformatics and Biology Insights, 2025

Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant.

Frohlich J et al.

Clinical Epigenetics, 2024

Genetics of human longevity: From variants to genes to pathways.

Smulders L et al.

Journal of Internal Medicine, 2024

Human centenarian-associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids.

Frohlich J et al.

Geroscience, 2023

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.

Simon M et al.

The Embo Journal, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."