Varaico: Literature-Extracted Genetic Variants

Gene:SIRT6
Variant:p.D63Y
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SIRT6

NM_016539.4:p.D63Y

Associated Papers

Mechanism of activation for the sirtuin 6 protein deacylase.

Klein MA et al.

The Journal of Biological Chemistry, 2020

SIRT6 is a DNA double-strand break sensor.

Onn L et al.

Elife, 2020

An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality.

Ferrer CM et al.

Genes & Development, 2018

Identification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.

Kugel S et al.

Cell Reports, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."