Varaico: Literature-Extracted Genetic Variants

Gene:SIX2
Variant:p.Q177R
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SIX2

NM_016932.5:p.Q177R

Associated Papers

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor.

Wegert J et al.

Genome Medicine, 2025

40340749 (PubMed )
Supplement: 13073_2025_1482_MOESM1_ESM.xlsx › Table_S2

Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor.

Murphy AJ et al.

Nature Communications, 2019

31862972 (PubMed )
Supplement: 41467_2019_13646_MOESM10_ESM.pdf

The genetic factors contributing to the development of Wilm's tumor and their clinical utility in its diagnosis and prognosis.

Bahrami A et al.

Journal of Cellular Physiology, 2018

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.

Ma X et al.

Nature, 2018

29489755 (PubMed )
Supplement: NIHMS939556-supplement-Table_2-7.xlsx › TableS5

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor.

Gadd S et al.

Nature Genetics, 2017

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

Perlman EJ et al.

Nature Communications, 2015

26635203 (PubMed )
Supplement: ncomms10013-s1.pdf

Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors.

Walz AL et al.

Cancer Cell, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."