Varaico: Literature-Extracted Genetic Variants

Gene:SKP2
Variant:p.L33R
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SKP2

NM_005983.4:p.L33R

Associated Papers

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2.

Enrico TP et al.

Elife, 2021

[Identification of the hemolytic transfusion reaction caused by lewis antibody using serological and molecular biological methods].

Hong XZ et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2008

CD28 costimulation mediates transcription of SKP2 and CKS1, the substrate recognition components of SCFSkp2 ubiquitin ligase that leads p27kip1 to degradation.

Appleman LJ et al.

Cell Cycle (georgetown, Tex.), 2006

Overexpressed Skp2 within 5p amplification detected by array-based comparative genomic hybridization is associated with poor prognosis of glioblastomas.

Saigusa K et al.

Cancer Science, 2005

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells.

Bhattacharya S et al.

Oncogene, 2003

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway.

Lisztwan J et al.

The Embo Journal, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."