Varaico: Literature-Extracted Genetic Variants

Gene:SLC10A1
Variant:p.I279T
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SLC10A1

NM_003049.4:p.I279T

Associated Papers

Amino acid substitutions at rheostat positions in the Na+/taurocholate cotransporting polypeptide substrate channel have pleiotropic effects.

Swint-Kruse L et al.

Protein Science : a Publication of the Protein Society, 2025

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.

Tremmel R et al.

International Journal of Molecular Sciences, 2022

35806468 (PubMed )
Supplement: ijms-23-07468-s001.zip › ijms-1789068-supplementary.pdf

NTCP Deficiency Affects the Levels of Circulating Bile Acids and Induces Osteoporosis.

Yang F et al.

Frontiers in Endocrinology, 2022

In Vitro Functional Characterization and in Silico Prediction of Rare Genetic Variation in the Bile Acid and Drug Transporter, Na+-Taurocholate Cotransporting Polypeptide (NTCP, SLC10A1).

Russell LE et al.

Molecular Pharmaceutics, 2020

Analysis of hepatitis B virus preS1 variability and prevalence of the rs2296651 polymorphism in a Spanish population.

Casillas R et al.

World Journal of Gastroenterology, 2018

Effect of S267F variant of NTCP on the patients with chronic hepatitis B.

Lee HW et al.

Scientific Reports, 2017

Homozygous p.Ser267Phe in SLC10A1 is associated with a new type of hypercholanemia and implications for personalized medicine.

Liu R et al.

Scientific Reports, 2017

28835676 (PubMed )
Supplement: 41598_2017_7012_MOESM1_ESM.doc

Comprehensive assessment showed no associations of variants at the SLC10A1 locus with susceptibility to persistent HBV infection among Southern Chinese.

Zhang Y et al.

Scientific Reports, 2017

A genetic variant of the NTCP gene is associated with HBV infection status in a Chinese population.

Yang J et al.

Bmc Cancer, 2016

The p.Ser267Phe variant in SLC10A1 is associated with resistance to chronic hepatitis B.

Peng L et al.

Hepatology (baltimore, Md.), 2015

Genetic polymorphisms in Na+-taurocholate co-transporting polypeptide (NTCP) and ileal apical sodium-dependent bile acid transporter (ASBT) and ethnic comparisons of functional variants of NTCP among Asian populations.

Pan W et al.

Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 2011

Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition.

Ho RH et al.

The Journal of Biological Chemistry, 2004

The solute carrier family 10 (SLC10): beyond bile acid transport.

Claro da Silva T et al.

Molecular Aspects of Medicine, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."