Associated Papers
Gene Editing of Pluripotent Stem Cell-Derived Hepatic Cells for Liver Disease Modeling and Therapeutic Development.
Lim D et al.
Biomolecules & Therapeutics, 2026
Structural mapping of NTCP distinguishes its dual functionality as a hepatitis B virus receptor and bile acid transporter.
Matsuzawa K et al.
Plos Pathogens, 2026
[Clinical and genetic characteristics of 14 children with sodium taurocholate co-transporting polypeptide deficiency].
Ma RX et al.
Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2025
Genetic Determinants of Leisure-Time Physical Activity in the Taiwanese Population: A Genome-Wide Association Study.
Hsu LA et al.
Medicine and Science in Sports and Exercise, 2025
Amino acid substitutions at rheostat positions in the Na+/taurocholate cotransporting polypeptide substrate channel have pleiotropic effects.
Swint-Kruse L et al.
Protein Science : a Publication of the Protein Society, 2025
Protective Role of the Sodium Taurocholate Cotransporting Polypeptide S267F Variant Against Hepatitis B Virus Infection and Cirrhosis in the Vietnamese Population.
Huy PX et al.
Journal of Medical Virology, 2025
Genomic sequencing as a key primary recommendation for neonatal hyperbilirubinemia: a population-based multicenter study.
Huang D et al.
Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025
Genetic study of intrahepatic cholestasis of pregnancy in Chinese women unveils East Asian etiology linked to historic HBV epidemic.
Liu Y et al.
Journal of Hepatology, 2025
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Genetic mapping of serum metabolome to chronic diseases among Han Chinese.
Cheng C et al.
Cell Genomics, 2025
The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.
Wang LY et al.
Innovation (cambridge (mass.)), 2025
Familial NTCPD presenting with persistent hypercholanemia and co-existing with a series of novel heterozygous mutations.
Wang M et al.
Clinics and Research in Hepatology and Gastroenterology, 2024
Population genetic admixture and evolutionary history in the Shandong Peninsula inferred from integrative modern and ancient genomic resources.
Su H et al.
Bmc Genomics, 2024
SLC10A1 rs2296651 variant (S267F mutation) predicts biochemical traits, hepatitis B virus infection susceptibility and the risk of gallstone disease.
Ko YL et al.
Molecular Genetics and Genomics : Mgg, 2024
Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation.
Xu ZM et al.
American Journal of Human Genetics, 2024
Molecular mechanisms of Na+-driven bile acid transport in human NTCP.
Lu X et al.
Biophysical Journal, 2024
Neonatal jaundice caused by compound mutations of SLC10A1 and a novel UGT1A1 gene.
Wang M et al.
Clinics and Research in Hepatology and Gastroenterology, 2024
Sodium taurocholate cotransporter polypeptide deficiency from two pairs of twins with homozygous and heterozygous of p.Ser267Phe variant, respectively: Case report.
Wang M et al.
Clinics and Research in Hepatology and Gastroenterology, 2024
The Born in Guangzhou Cohort Study enables generational genetic discoveries.
Huang S et al.
Nature, 2024
When the same treatment has different response: The role of pharmacogenomics in statin therapy.
Zheng E et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2024
The application of whole-exome sequencing in the early diagnosis of rare genetic diseases in children: a study from Southeastern China.
Lai G et al.
Frontiers in Pediatrics, 2024
Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.
Zhang T et al.
Peerj, 2024
Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.
Chen CY et al.
Cell Genomics, 2023
Identification of a bile acid and bile salt metabolism-related lncRNA signature for predicting prognosis and treatment response in hepatocellular carcinoma.
Cui H et al.
Scientific Reports, 2023
Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in Humans.
Pan Q et al.
Cellular and Molecular Gastroenterology and Hepatology, 2023
Role of Hepatocyte Transporters in Drug-Induced Liver Injury (DILI)-In Vitro Testing.
Tátrai P et al.
Pharmaceutics, 2022
Thyroid Hormone Transporters in Pregnancy and Fetal Development.
Chen Z et al.
International Journal of Molecular Sciences, 2022
Oligomerization of the HBV/HDV functional receptor NTCP expressed in Sf9 insect cell.
Qin T et al.
Biochimica Et Biophysica Acta. General Subjects, 2022
The S267F variant of sodium taurocholate co-transporting polypeptide is strongly associated with resistance to chronic hepatitis B and high level of serum total bile acids.
Huang J et al.
Liver Research (beijing, China), 2022
Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.
Tremmel R et al.
International Journal of Molecular Sciences, 2022
Tyrosine 146 of the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP) Is Essential for Its Hepatitis B Virus (HBV) Receptor Function and HBV Entry into Hepatocytes.
Zakrzewicz D et al.
Viruses, 2022
Structural basis of sodium-dependent bile salt uptake into the liver.
Goutam K et al.
Nature, 2022
Structure of the bile acid transporter and HBV receptor NTCP.
Asami J et al.
Nature, 2022
Structural insights into the HBV receptor and bile acid transporter NTCP.
Park JH et al.
Nature, 2022
Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors.
Maekawa K et al.
Drug Metabolism and Pharmacokinetics, 2022
Structural Plasticity Is a Feature of Rheostat Positions in the Human Na+/Taurocholate Cotransporting Polypeptide (NTCP).
Ruggiero MJ et al.
International Journal of Molecular Sciences, 2022
Sodium taurocholate co-transporting polypeptide deficiency.
Schneider AL et al.
Clinics and Research in Hepatology and Gastroenterology, 2022
Molecular Epidemiology of Na+-Taurocholate Cotransporting Polypeptide Deficiency in Guangdong Province, China: A Pilot Study by Screening for Four Prevalent Variants of the Causative Gene SLC10A1.
Li H et al.
Frontiers in Genetics, 2022
NTCP Deficiency Affects the Levels of Circulating Bile Acids and Induces Osteoporosis.
Yang F et al.
Frontiers in Endocrinology, 2022
Whole-exome sequencing expands the roles of novel mutations of organic anion transporting polypeptide, ATP-binding cassette transporter, and receptor genes in intrahepatic cholestasis of pregnancy.
Liu X et al.
Frontiers in Genetics, 2022
Case report: Prenatal diagnosis of fetal non-compaction cardiomyopathy with bradycardia accompanied by de novo CALM2 mutation.
Zhang W et al.
Frontiers in Pediatrics, 2022
De novo mutation loci and clinical analysis in a child with sodium taurocholate cotransport polypeptide deficiency: A case report.
Liu HY et al.
World Journal of Clinical Cases, 2021