Associated Papers
Methotrexate recognition by the human reduced folate carrier SLC19A1.
Wright NJ et al.
Nature, 2022
The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment.
Rudin S et al.
Genomics, Proteomics & Bioinformatics, 2017
Residues 45 and 404 in the murine reduced folate carrier may interact to alter carrier binding and mobility.
Zhao R et al.
Biochimica Et Biophysica Acta, 2003
Reduced folate carrier: biochemistry and molecular biology of the normal and methotrexate-resistant cell.
Bosson G
British Journal of Biomedical Science, 2003
Role of the E45K-reduced folate carrier gene mutation in methotrexate resistance in human leukemia cells.
Gifford AJ et al.
Leukemia, 2002
Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate.
Tse A et al.
The Journal of Biological Chemistry, 1998
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