Associated Papers
Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1.
Römer S et al.
The Journal of Biological Chemistry, 2025
Structural insights into human organic cation transporter 1 transport and inhibition.
Zhang S et al.
Cell Discovery, 2024
38485705 (PubMed )
Supplement: 41421_2024_664_MOESM11_ESM.pdf
Structural basis of promiscuous substrate transport by Organic Cation Transporter 1.
Zeng YC et al.
Nature Communications, 2023
Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Suo Y et al.
Nature Structural & Molecular Biology, 2023
Amino acids in transmembrane helix 1 confer major functional differences between human and mouse orthologs of the polyspecific membrane transporter OCT1.
Meyer MJ et al.
The Journal of Biological Chemistry, 2022
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