Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A1
Variant:p.S52S
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SLC22A1

NM_003057.3:p.S52S

Associated Papers

Tramadol-related fatalities: Metabolic ratios & SNPs/INDELs belonging to UGT1A8, UGT2B7, ABCC2, and SLC22A1.

Aly SM et al.

Forensic Science International. Genetics, 2025

Insights Into Genetic Variations of the OCT1 Gene in Metformin Poor Responders Among Bangladeshi Type 2 Diabetic Patients.

Begum R et al.

Advances in Pharmacological and Pharmaceutical Sciences, 2025

Genetic Variants of ABC and SLC Transporter Genes and Chronic Myeloid Leukaemia: Impact on Susceptibility and Prognosis.

Alves R et al.

International Journal of Molecular Sciences, 2022

36077209 (PubMed )
Supplement: ijms-23-09815-s001.zip › ijms-1852648-supplementary.pdf

Role of human organic cation transporter-1 (OCT-1/SLC22A1) in modulating the response to metformin in patients with type 2 diabetes.

Kawoosa F et al.

Bmc Endocrine Disorders, 2022

Association of SLC22A1,SLCO1B3 Drug Transporter Polymorphisms and Smoking with Disease Risk and Cytogenetic Response to Imatinib in Patients with Chronic Myeloid Leukemia.

Mohammadi F et al.

Laboratory Medicine, 2021

Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.

Aboul-Soud MAM et al.

Saudi Journal of Biological Sciences, 2021

33424349 (PubMed )
Supplement: mmc1.xlsx › Sheet1

Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical Practice.

Venkatachalapathy P et al.

Pharmacogenomics and Personalized Medicine, 2021

Targeted next generation sequencing as a tool for precision medicine.

Gulilat M et al.

Bmc Medical Genomics, 2019

31159795 (PubMed )
Supplement: 12920_2019_527_MOESM1_ESM.xlsx › Table_S6

The significance of enzyme and transporter polymorphisms for imatinib plasma levels and achieving an optimal response in chronic myeloid leukemia patients.

Belohlavkova P et al.

Archives of Medical Science : Ams, 2018

Genetic polymorphisms of organic cation transporter 1 (OCT1) and responses to metformin therapy in individuals with type 2 diabetes: A systematic review.

Mofo Mato EP et al.

Medicine, 2018

Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder.

Medhasi S et al.

Neuropsychiatric Disease and Treatment, 2016

Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.

Herraez E et al.

Hepatology (baltimore, Md.), 2013

Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia.

Takahashi N et al.

Journal of Human Genetics, 2010

Identification and functional characterization of genetic variants of human organic cation transporters in a Korean population.

Kang HJ et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."