Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A1
Variant:p.E386Q
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SLC22A1

NM_003057.3:p.E386Q

Associated Papers

Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1.

Römer S et al.

The Journal of Biological Chemistry, 2025

Targeted mutagenesis of negatively charged amino acids outlining the substrate translocation path within the human organic cation transporter 3.

Redeker KM et al.

Biochemical Pharmacology, 2024

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."