Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A1
Variant:p.E386A
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SLC22A1

NM_003057.3:p.E386A

Associated Papers

The divergent roles of tryptophans W354 and W217 in OCT1 transport: Similar localization, distinct functions.

Römer S et al.

The Journal of Biological Chemistry, 2025

Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1.

Römer S et al.

The Journal of Biological Chemistry, 2025

Structural insights into human organic cation transporter 1 transport and inhibition.

Zhang S et al.

Cell Discovery, 2024

38485705 (PubMed )
Supplement: 41421_2024_664_MOESM13_ESM.pdf

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.

Suo Y et al.

Nature Structural & Molecular Biology, 2023

Molecular basis of polyspecific drug binding and transport by OCT1 and OCT2.

Suo Y et al.

Biorxiv : the Preprint Server for Biology, 2023

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."