Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A16
Variant:p.H49R
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SLC22A16

NM_033125.4:p.H49R

Associated Papers

Human iPSC-based breast cancer model identifies S100P-dependent cancer stemness induced by BRCA1 mutation.

Liu J et al.

Science Advances, 2025

40712032 (PubMed )
Supplement: sciadv.adi2370_tables_s8_and_s9.zip › adi2370_table_s9.xlsx › BRCA1-mutant_corrected_iPSC

Natural History of Germline BRCA1 Mutated and BRCA Wild-type Triple-negative Breast Cancer.

Gardi N et al.

Cancer Research Communications, 2024

38315150 (PubMed )
Supplement: crc-23-0277-s13.xlsx › Sheet1

Pharmacogenetics of Drug Metabolism: The Role of Gene Polymorphism in the Regulation of Doxorubicin Safety and Efficacy.

Bagdasaryan AA et al.

Cancers, 2022

Role of Pharmacogenetics in the Treatment of Acute Myeloid Leukemia: Systematic Review and Future Perspectives.

Pinto-Merino Á et al.

Pharmaceutics, 2022

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM15_ESM.xlsx › Supplementary_Data_12

Variants of SLC22A16 Predict the Efficacy of Platinum Combination Chemotherapy in Advanced Non-small-cell Lung Cancer.

Takeuchi A et al.

Anticancer Research, 2020

The genetic landscape of the human solute carrier (SLC) transporter superfamily.

Schaller L et al.

Human Genetics, 2019

Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review.

Kulma I et al.

Cancer Chemotherapy and Pharmacology, 2019

Genome sequencing analysis of blood cells identifies germline haplotypes strongly associated with drug resistance in osteosarcoma patients.

Bhuvaneshwar K et al.

Bmc Cancer, 2019

30991985 (PubMed )
Supplement: 12885_2019_5474_MOESM4_ESM.xlsx › 2016NovDec12_2016Dec12_85_15_GL

Whole exome sequencing in three families segregating a pediatric case of sarcoidosis.

Calender A et al.

Bmc Medical Genomics, 2018

29510755 (PubMed )
Supplement: 12920_2018_338_MOESM6_ESM.xlsx › T1

Pharmacogenetics of toxicity of 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients.

Tecza K et al.

Oncotarget, 2018

29507678 (PubMed )
Supplement: oncotarget-09-9114-s002.xlsx › Sheet1

Genotypes Affecting the Pharmacokinetics of Anticancer Drugs.

Bertholee D et al.

Clinical Pharmacokinetics, 2017

Candidate Gene Association Studies of Anthracycline-induced Cardiotoxicity: A Systematic Review and Meta-analysis.

Leong SL et al.

Scientific Reports, 2017

28232737 (PubMed )
Supplement: 41598_2017_75_MOESM1_ESM.pdf

Validating the pharmacogenomics of chemotherapy-induced cardiotoxicity: What is missing?

Magdy T et al.

Pharmacology & Therapeutics, 2016

Pharmacogenetics of irinotecan, doxorubicin and docetaxel transporters in Asian and Caucasian cancer patients: a comparative review.

Chen S et al.

Drug Metabolism Reviews, 2016

Genetic polymorphisms and response to 5-fluorouracil, doxorubicin and cyclophosphamide chemotherapy in breast cancer patients.

Tecza K et al.

Oncotarget, 2016

Generalized Multifactor Dimensionality Reduction (GMDR) Analysis of Drug-Metabolizing Enzyme-Encoding Gene Polymorphisms may Predict Treatment Outcomes in Indian Breast Cancer Patients.

Agarwal G et al.

World Journal of Surgery, 2016

Pharmacogenetics driving personalized medicine: analysis of genetic polymorphisms related to breast cancer medications in Italian isolated populations.

Cocca M et al.

Journal of Translational Medicine, 2016

26801900 (PubMed )
Supplement: 12967_2016_778_MOESM3_ESM.xls › Sheet1

Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine.

Simeon V et al.

International Journal of Molecular Sciences, 2015

26263974 (PubMed )
Supplement: ijms-16-17514-s001.pdf

Pharmacokinetics and pharmacogenomics of daunorubicin in children: a report from the Children's Oncology Group.

Thompson P et al.

Cancer Chemotherapy and Pharmacology, 2014

Pharmacogenetics of genes across the doxorubicin pathway.

Jamieson D et al.

Expert Opinion on Drug Metabolism & Toxicology, 2011

Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide.

Bray J et al.

British Journal of Cancer, 2010

Pharmacogenetics influence treatment efficacy in childhood acute lymphoblastic leukemia.

Davidsen ML et al.

Journal of Pediatric Hematology/oncology, 2008

Novel SLC22A16 polymorphisms and influence on doxorubicin pharmacokinetics in Asian breast cancer patients.

Lal S et al.

Pharmacogenomics, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."