Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A3
Variant:p.T400I
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SLC22A3

NM_021977.4:p.T400I

Associated Papers

Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape.

Pearce B et al.

Molecular Biology Reports, 2023

Structural basis of organic cation transporter-3 inhibition.

Khanppnavar B et al.

Nature Communications, 2022

36344565 (PubMed )
Supplement: 41467_2022_34284_MOESM1_ESM.pdf

The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition.

Zazuli Z et al.

International Journal of Molecular Sciences, 2020

Association between Polymorphisms of OCT1 and Metabolic Response to Metformin in Women with Polycystic Ovary Syndrome.

Chang HH et al.

International Journal of Molecular Sciences, 2019

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Lozano E et al.

Journal of Personalized Medicine, 2018

Effects of the genetic variants of organic cation transporters 1 and 3 on the pharmacokinetics of metformin in Jordanians.

Hakooz N et al.

Drug Metabolism and Personalized Therapy, 2017

Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.

Zhou F et al.

Advanced Drug Delivery Reviews, 2017

Influences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects.

Yoon H et al.

The Aaps Journal, 2013

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin.

Chen L et al.

Pharmacogenetics and Genomics, 2010

Functional analysis of human organic cation transporter OCT3 (SLC22A3) polymorphisms.

Sakata T et al.

Journal of Pharmacological Sciences, 2010

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.

Nies AT et al.

Hepatology (baltimore, Md.), 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."