Associated Papers
Dissecting the Genetic Architecture of Intracranial Aneurysms.
Adkar SS et al.
Circulation. Genomic and Precision Medicine, 2025
Contrastive sequence signatures between the both sides of a recombination spot reveal an adaptation at PPARD locus from standing variation for pleiotropy since out-of-Africa dispersal.
Shou W et al.
Bmc Genomics, 2025
Carnitine traffic and human fertility.
Mazza T et al.
Biochemical Pharmacology, 2024
VCAT: an integrated variant function annotation tools.
Huang B et al.
Human Genetics, 2024
Exome Sequence Data of Eight SLC Transporters Reveal That SLC22A1 and SLC22A3 Variants Alter Metformin Pharmacokinetics and Glycemic Control.
Morales-Rivera MI et al.
Pharmaceuticals (basel, Switzerland), 2024
Atomistic description of the OCTN1 recognition mechanism via in silico methods.
Ben Mariem O et al.
Plos One, 2024
Impact of genetic variants in the solute carrier (SLC) genes encoding drug uptake transporters on the response to anticancer chemotherapy.
Marin JJG et al.
Cancer Drug Resistance (alhambra, Calif.), 2024
Quantitative thresholds for variant enrichment in 13,845 cases: improving pathogenicity classification in genetic hearing loss.
Liu S et al.
Genome Medicine, 2023
The Role of Organic Cation Transporters in the Pharmacokinetics, Pharmacodynamics and Drug-Drug Interactions of Tyrosine Kinase Inhibitors.
Xiu F et al.
International Journal of Molecular Sciences, 2023
Exome variants associated with asthma and allergy.
Wjst M
Scientific Reports, 2022
Lack of impact of OCTN1 gene polymorphisms on clinical outcomes of gabapentinoids in Pakistani patients with neuropathic pain.
Shaheen A et al.
Plos One, 2022
Functional screen of inflammatory bowel disease genes reveals key epithelial functions.
Ntunzwenimana JC et al.
Genome Medicine, 2021
Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.
Meisel P et al.
Clinical Oral Investigations, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
Transporter tandems: precise tools for normalizing active transporter in the plasma membrane.
Tschirka J et al.
The Biochemical Journal, 2020
Currently favored sampling practices for tumor sequencing can produce optimal results in the clinical setting.
Pongor LS et al.
Scientific Reports, 2020
The genetic landscape of the human solute carrier (SLC) transporter superfamily.
Schaller L et al.
Human Genetics, 2019
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
Genetic Studies of Inflammatory Bowel Disease-Focusing on Asian Patients.
Park SC et al.
Cells, 2019
Pharmacogenetics-based population pharmacokinetic analysis of gabapentin in patients with chronic pain: Effect of OCT2 and OCTN1 gene polymorphisms.
Yamamoto PA et al.
Basic & Clinical Pharmacology & Toxicology, 2019
Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.
Lozano E et al.
Journal of Personalized Medicine, 2018
Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.
Zhou F et al.
Advanced Drug Delivery Reviews, 2017
Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis.
Dujic T et al.
Clinical Pharmacology and Therapeutics, 2017
Association study between OCTN1 functional haplotypes and Crohn's disease in a Korean population.
Jung ES et al.
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2017
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Surendran P et al.
Nature Genetics, 2016
L503F variant of carnitine/organic cation transporter 1 efficiently transports metformin and other biguanides.
Futatsugi A et al.
The Journal of Pharmacy and Pharmacology, 2016
Pharmacogenetics of BCR/ABL Inhibitors in Chronic Myeloid Leukemia.
Polillo M et al.
International Journal of Molecular Sciences, 2015
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genes.
Prescott NJ et al.
Plos Genetics, 2015
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes.
Bavarva JH et al.
Oncotarget, 2014
Identification and Functional Characterization of Novel Genetic Variations in the OCTN1 Promoter.
Park HJ et al.
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2014
Genetic variants in the JAK1 gene confer higher risk of Behcet's disease with ocular involvement in Han Chinese.
Hou S et al.
Human Genetics, 2013
NOD2 mutations affect muramyl dipeptide stimulation of human B lymphocytes and interact with other IBD-associated genes.
Lin Z et al.
Digestive Diseases and Sciences, 2013
Functional analysis of novel variants in the organic cation/ergothioneine transporter 1 identified in Singapore populations.
Toh DS et al.
Molecular Pharmaceutics, 2013
Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes.
Christodoulou K et al.
Gut, 2013
Enzymes involved in L-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: implications for gut health.
Shekhawat PS et al.
Journal of Crohn's & Colitis, 2013
Influences of organic cation transporter polymorphisms on the population pharmacokinetics of metformin in healthy subjects.
Yoon H et al.
The Aaps Journal, 2013
Gene genealogies for genetic association mapping, with application to Crohn's disease.
Burkett KM et al.
Frontiers in Genetics, 2013
Contribution of higher risk genes and European admixture to Crohn's disease in African Americans.
Wang MH et al.
Inflammatory Bowel Diseases, 2012
Single-nucleotide polymorphisms in inflammatory bowel disease.
Neuman MG et al.
Translational Research : the Journal of Laboratory and Clinical Medicine, 2012