Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A6
Variant:p.R454Q
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SLC22A6

NM_153276.3:p.R454Q

Associated Papers

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

The substrate and inhibitor binding mechanism of polyspecific transporter OAT1 revealed by high-resolution cryo-EM.

Dou T et al.

Nature Structural & Molecular Biology, 2023

Substrate binding and lipid-mediated allostery in the human organic anion transporter 1 at the atomic-scale.

Janaszkiewicz A et al.

Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 2023

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Genetic Diversity in Drug Transporters: Impact in African Populations.

Rajman I et al.

Clinical and Translational Science, 2020

Genetic Heterogeneity of SLC22 Family of Transporters in Drug Disposition.

Lozano E et al.

Journal of Personalized Medicine, 2018

Screening of genetic variations of SLC15A2, SLC22A1, SLC22A2 and SLC22A6 genes.

Cheong HS et al.

Journal of Human Genetics, 2011

Identification of genetic polymorphisms of human OAT1 and OAT2 genes and their relationship to hOAT2 expression in human liver.

Shin HJ et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

Hepatocyte nuclear factor-4{alpha} regulates the human organic anion transporter 1 gene in the kidney.

Ogasawara K et al.

American Journal of Physiology. Renal Physiology, 2007

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).

Fujita T et al.

Pharmacogenetics and Genomics, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."