Varaico: Literature-Extracted Genetic Variants

Gene:SLC22A6
Variant:p.Y230F
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SLC22A6

NM_153276.3:p.Y230F

Associated Papers

Cryo-EM structures of human OAT1 reveal drug binding and inhibition mechanisms.

Jeon HM et al.

Structure (london, England : 1993), 2025

Structural insights into human polyspecific organic anion transporters OAT1 and OAT4.

Zhang W et al.

Cell Reports, 2025

Structures and membrane interactions of human OAT1 in complex with clinical used drugs.

Wu X et al.

Science Advances, 2025

Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.

Parker JL et al.

Nature Structural & Molecular Biology, 2023

Structural Insights into the Atomistic Mechanisms of Uric Acid Recognition and Translocation of Human Urate Anion Transporter 1.

Zhao Z et al.

Acs Omega, 2020

Biochemical studies on the structure-function relationship of major drug transporters in the ATP-binding cassette family and solute carrier family.

Hong M

Advanced Drug Delivery Reviews, 2017

A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport.

Perry JL et al.

The Journal of Biological Chemistry, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."