Varaico: Literature-Extracted Genetic Variants

Gene:SLC25A1
Variant:p.R5P
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SLC25A1

NM_005984.5:p.R5P

Associated Papers

Targeting IMPDH to inhibit SAMHD1 in KMT2A-rearranged leukaemia.

Klootsema Y et al.

Cell Cycle (georgetown, Tex.), 2025

Conformational changes in ammonia-channeling glutamine amidotransferases.

Mouilleron S et al.

Current Opinion in Structural Biology, 2007

Pyrimidine nucleotides impair phosphoribosylpyrophosphate (PRPP) synthetase subunit aggregation by sequestering magnesium. A mechanism for the decreased PRPP synthetase activity in hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency.

Lachant NA et al.

Biochimica Et Biophysica Acta, 1989

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."