Associated Papers
Hearing Loss and Audiogenic Seizures Induced by Hypofunctional Prestin Variants.
Takahashi S et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2025
The frequency dependence of prestin-mediated fast electromotility for mammalian cochlear amplification.
Takahashi S et al.
Biorxiv : the Preprint Server for Biology, 2024
The pathogenic roles of the p.R130S prestin variant in DFNB61 hearing loss.
Takahashi S et al.
The Journal of Physiology, 2024
The molecular principles underlying diverse functions of the SLC26 family of proteins.
Takahashi S et al.
Biorxiv : the Preprint Server for Biology, 2023
The pathogenic roles of the p.R130S prestin variant in DFNB61 hearing loss.
Takahashi S et al.
Biorxiv : the Preprint Server for Biology, 2023
Prestin's fast motor kinetics is essential for mammalian cochlear amplification.
Takahashi S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2023
Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility.
Futamata H et al.
Nature Communications, 2022
The conformational cycle of prestin underlies outer-hair cell electromotility.
Bavi N et al.
Nature, 2021
Deletion of exons 17 and 18 in prestin's STAS domain results in loss of function.
Takahashi S et al.
Scientific Reports, 2019
The R130S mutation significantly affects the function of prestin, the outer hair cell motor protein.
Takahashi S et al.
Journal of Molecular Medicine (berlin, Germany), 2016
Abnormal mRNA splicing but normal auditory brainstem response (ABR) in mice with the prestin (SLC26A5) IVS2-2A>G mutation.
Zhang J et al.
Mutation Research, 2016
The V499G/Y501H mutation impairs fast motor kinetics of prestin and has significance for defining functional independence of individual prestin subunits.
Homma K et al.
The Journal of Biological Chemistry, 2013
Normal hearing sensitivity at low-to-middle frequencies with 34% prestin-charge density.
Yamashita T et al.
Plos One, 2012
Structural rearrangements of the motor protein prestin revealed by fluorescence resonance energy transfer.
Gleitsman KR et al.
American Journal of Physiology. Cell Physiology, 2009
alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.
Legendre K et al.
Journal of Cell Science, 2008
The C-terminus of prestin influences nonlinear capacitance and plasma membrane targeting.
Zheng J et al.
Journal of Cell Science, 2005