Varaico: Literature-Extracted Genetic Variants

Gene:SLC28A3
Variant:p.C602S
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SLC28A3

NM_001199633.2:p.C602S

Associated Papers

The human concentrative nucleoside transporter-3 C602R variant shows impaired sorting to lipid rafts and altered specificity for nucleoside-derived drugs.

Errasti-Murugarren E et al.

Molecular Pharmacology, 2010

A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3.

Slugoski MD et al.

The Journal of Biological Chemistry, 2008

Functional characterization of a nucleoside-derived drug transporter variant (hCNT3C602R) showing altered sodium-binding capacity.

Errasti-Murugarren E et al.

Molecular Pharmacology, 2008

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