Associated Papers
Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway.
Boulter E et al.
Nature Communications, 2018
The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane.
Fort J et al.
The Journal of Biological Chemistry, 2007
CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation.
Henderson NC et al.
The Journal of Biological Chemistry, 2004
Distinct domains of CD98hc regulate integrins and amino acid transport.
Fenczik CA et al.
The Journal of Biological Chemistry, 2001
Beta1 integrins show specific association with CD98 protein in low density membranes.
Kolesnikova TV et al.
Bmc Biochemistry, 2001
The heterodimeric amino acid transporter 4F2hc/LAT1 is associated in Xenopus oocytes with a non-selective cation channel that is regulated by the serine/threonine kinase sgk-1.
Wagner CA et al.
The Journal of Physiology, 2000
Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.
Torrents D et al.
The Journal of Biological Chemistry, 1998
Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond.
Pfeiffer R et al.
Febs Letters, 1998
The amino acid transport system y+L/4F2hc is a heteromultimeric complex.
Estévez R et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 1998
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