Associated Papers
Functional role of serine 318 of the proton-coupled folate transporter in methotrexate transport.
Narawa T et al.
Drug Metabolism and Pharmacokinetics, 2021
A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation.
Zhan HQ et al.
The Journal of Biological Chemistry, 2020
Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation.
Aluri S et al.
The Journal of Biological Chemistry, 2019
Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1).
Aluri S et al.
American Journal of Physiology. Cell Physiology, 2018
The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.
Zhao R et al.
Molecular Aspects of Medicine, 2017
iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.
Wang M et al.
Scientific Reports, 2016
Reversible pancytopenia and immunodeficiency in a patient with hereditary folate malabsorption.
Erlacher M et al.
Pediatric Blood & Cancer, 2015
Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method.
Shin DS et al.
American Journal of Physiology. Cell Physiology, 2013
Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1).
Zhao R et al.
American Journal of Physiology. Cell Physiology, 2012
A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding.
Shin DS et al.
American Journal of Physiology. Cell Physiology, 2012
Identification and functional impact of homo-oligomers of the human proton-coupled folate transporter.
Hou Z et al.
The Journal of Biological Chemistry, 2012
Prevalence of a loss-of-function mutation in the proton-coupled folate transporter gene (PCFT-SLC46A1) causing hereditary folate malabsorption in Puerto Rico.
Mahadeo KM et al.
The Journal of Pediatrics, 2011
Random mutagenesis of the proton-coupled folate transporter (SLC46A1), clustering of mutations, and the bases for associated losses of function.
Zhao R et al.
The Journal of Biological Chemistry, 2011
Identification of novel mutations in the proton-coupled folate transporter (PCFT-SLC46A1) associated with hereditary folate malabsorption.
Shin DS et al.
Molecular Genetics and Metabolism, 2011
Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption.
Shin DS et al.
Blood, 2010