Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A3
Variant:p.D313N
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SLC6A3

NM_001044.5:p.D313N

Associated Papers

Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters.

Liang YJ et al.

Journal of Neurochemistry, 2009

Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.

Schmitt KC et al.

Journal of Neurochemistry, 2008

Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.

Chen N et al.

Journal of Neurochemistry, 2004

Na+ and the substrate permeation pathway in dopamine transporters.

Chen N et al.

European Journal of Pharmacology, 2003

Cationic interactions at the human dopamine transporter reveal binding conformations for dopamine distinguishable from those for the cocaine analog 2 alpha-carbomethoxy-3 alpha-(4-fluorophenyl)tropane.

Chen N et al.

Journal of Neurochemistry, 2002

The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis.

Chen N et al.

Journal of Neurochemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."