Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A3
Variant:p.Y102*
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SLC6A3

NM_001044.5:p.Y102*

Associated Papers

Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter.

Aggarwal S et al.

Biomedicines, 2021

Trimerization of dopamine transporter triggered by AIM-100 binding: Molecular mechanism and effect of mutations.

Cheng MH et al.

Neuropharmacology, 2019

Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes.

Herborg F et al.

The Journal of Biological Chemistry, 2018

A conserved salt bridge between transmembrane segments 1 and 10 constitutes an extracellular gate in the dopamine transporter.

Pedersen AV et al.

The Journal of Biological Chemistry, 2014

Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation.

Dehnes Y et al.

Neurochemistry International, 2014

Glycine transporter dimers: evidence for occurrence in the plasma membrane.

Bartholomäus I et al.

The Journal of Biological Chemistry, 2008

A triple mutation in the second transmembrane domain of mouse dopamine transporter markedly decreases sensitivity to cocaine and methylphenidate.

Chen R et al.

Journal of Neurochemistry, 2005

Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding.

Loland CJ et al.

The Journal of Biological Chemistry, 2004

Zn(2+) site engineering at the oligomeric interface of the dopamine transporter.

Norgaard-Nielsen K et al.

Febs Letters, 2002

Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.

Whitehead RE et al.

Journal of Neurochemistry, 2001

Transport-dependent accessibility of a cytoplasmic loop cysteine in the human dopamine transporter.

Chen N et al.

The Journal of Biological Chemistry, 2000

Cocaine alters the accessibility of endogenous cysteines in putative extracellular and intracellular loops of the human dopamine transporter.

Ferrer JV et al.

Proceedings of the National Academy of Sciences of the United States of America, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."