Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A4
Variant:p.P601A
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SLC6A4

NM_001045.6:p.P601A

Associated Papers

Allosteric Inhibition and Pharmacochaperoning of the Serotonin Transporter by the Antidepressant Drugs Trazodone and Nefazodone.

El-Kasaby A et al.

Molecular Pharmacology, 2024

Thermal Unfolding of the Human Serotonin Transporter: Differential Effect by Stabilizing and Destabilizing Mutations and Cholesterol on Thermodynamic and Kinetic Stability.

Ponleitner M et al.

Molecular Pharmacology, 2022

Molecular and Clinical Repercussions of GABA Transporter 1 Variants Gone Amiss: Links to Epilepsy and Developmental Spectrum Disorders.

Fischer FP et al.

Frontiers in Molecular Biosciences, 2022

A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.

Koban F et al.

The Journal of Biological Chemistry, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."