Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A4
Variant:p.I575T
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SLC6A4

NM_001045.6:p.I575T

Associated Papers

Modulation of Autism-Associated Serotonin Transporters by Palmitoylation: Insights into the Molecular Pathogenesis and Targeted Therapies for Autism Spectrum Disorder.

Brown CR et al.

Acs Chemical Neuroscience, 2025

The allosteric citalopram binding site differentially interferes with neuronal firing rate and SERT trafficking in serotonergic neurons.

Matthäus F et al.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 2016

An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: kinetic binding studies with the ALI/VFL-SI/TT mutant.

Zhong H et al.

Neuroscience Letters, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."