Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A4
Variant:p.F465L
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SLC6A4

NM_001045.6:p.F465L

Associated Papers

Modulation of Autism-Associated Serotonin Transporters by Palmitoylation: Insights into the Molecular Pathogenesis and Targeted Therapies for Autism Spectrum Disorder.

Brown CR et al.

Acs Chemical Neuroscience, 2025

Modulation of autism-associated serotonin transporters by palmitoylation: Insights into the molecular pathogenesis and targeted therapies for autism spectrum disorder.

Brown CR et al.

Biorxiv : the Preprint Server for Biology, 2025

DNA Sequence Variations Affecting Serotonin Transporter Transcriptional Regulation and Activity: Do They Impact Alcohol Addiction?

Ferraguti G et al.

International Journal of Molecular Sciences, 2024

Exploring the Structural and Functional Effects of Nonsynonymous SNPs in the Human Serotonin Transporter Gene Through In Silico Approaches.

Mia MA et al.

Bioinformatics and Biology Insights, 2022

Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits.

Bhat S et al.

Pharmacology & Therapeutics, 2021

Rare Opportunities for Insights Into Serotonergic Contributions to Brain and Bowel Disorders: Studies of the SERT Ala56 Mouse.

Stilley SE et al.

Frontiers in Cellular Neuroscience, 2021

The serotonin system in autism spectrum disorder: From biomarker to animal models.

Muller CL et al.

Neuroscience, 2016

Defining the blanks--pharmacochaperoning of SLC6 transporters and ABC transporters.

Chiba P et al.

Pharmacological Research, 2014

Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome.

Campbell NG et al.

Molecular Autism, 2013

Natural and engineered coding variation in antidepressant-sensitive serotonin transporters.

Ye R et al.

Neuroscience, 2011

Regulation of monoamine transporters: Role of transporter phosphorylation.

Ramamoorthy S et al.

Pharmacology & Therapeutics, 2011

Modeling rare gene variation to gain insight into the oldest biomarker in autism: construction of the serotonin transporter Gly56Ala knock-in mouse.

Veenstra-Vanderweele J et al.

Journal of Neurodevelopmental Disorders, 2009

SLC6A4 variation and citalopram response.

Mrazek DA et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2009

Enhanced activity of human serotonin transporter variants associated with autism.

Prasad HC et al.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 2009

Population-based association study and contrasting linkage disequilibrium pattern reveal genetic association of SLC6A4 with autism in the Indian population from West Bengal.

Guhathakurta S et al.

Brain Research, 2008

A large-scale screen for coding variants in SERT/SLC6A4 in autism spectrum disorders.

Sakurai T et al.

Autism Research : Official Journal of the International Society for Autism Research, 2008

5-HTTLPR Genotype-Specific Phenotype in Children and Adolescents With Autism.

Brune CW et al.

The American Journal of Psychiatry, 2006

Allelic heterogeneity at the serotonin transporter locus (SLC6A4) confers susceptibility to autism and rigid-compulsive behaviors.

Sutcliffe JS et al.

American Journal of Human Genetics, 2005

SLC6 transporters: structure, function, regulation, disease association and therapeutics.

Pramod AB et al.

Molecular Aspects of Medicine, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."