Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A4
Variant:p.S438T
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SLC6A4

NM_001045.6:p.S438T

Associated Papers

Structural basis of vilazodone dual binding mode to the serotonin transporter.

Kalenderoglou IE et al.

Nature Communications, 2025

Structural basis of vilazodone dual binding mode to the serotonin transporter.

Kalenderoglou IE et al.

Research Square, 2025

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.

Plenge P et al.

Nature Communications, 2021

Importance of the Extracellular Loop 4 in the Human Serotonin Transporter for Inhibitor Binding and Substrate Translocation.

Rannversson H et al.

The Journal of Biological Chemistry, 2015

The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport.

Felts B et al.

The Journal of Biological Chemistry, 2014

Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter.

Andersen J et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."