Associated Papers
Structural basis of vilazodone dual binding mode to the serotonin transporter.
Kalenderoglou IE et al.
Nature Communications, 2025
Structural basis of vilazodone dual binding mode to the serotonin transporter.
Kalenderoglou IE et al.
Research Square, 2025
The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter.
Plenge P et al.
Nature Communications, 2021
Binding of mazindol and analogs to the human serotonin and dopamine transporters.
Severinsen K et al.
Molecular Pharmacology, 2014
Extracellular loop 3 of the noradrenaline transporter contributes to substrate and inhibitor selectivity.
Lynagh T et al.
Naunyn-schmiedeberg's Archives of Pharmacology, 2014
The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter.
Sarker S et al.
Molecular Pharmacology, 2010
Transmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.
Field JR et al.
The Journal of Biological Chemistry, 2010
Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter.
Andersen J et al.
The Journal of Biological Chemistry, 2010
Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites.
Plenge P et al.
European Journal of Pharmacology, 2007
Homology modeling of the serotonin transporter: insights into the primary escitalopram-binding site.
Jørgensen AM et al.
Chemmedchem, 2007
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Henry LK et al.
The Journal of Biological Chemistry, 2006
High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol.
Barker EL et al.
The Journal of Biological Chemistry, 1998
Select a paper to view details