Varaico: Literature-Extracted Genetic Variants

Gene:SLC6A4
Variant:p.T81A
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SLC6A4

NM_001045.6:p.T81A

Associated Papers

Breaking the rules of SLC6 transporters: Export of the human creatine transporter-1 from the endoplasmic reticulum is supported by its N-terminus.

Ün D et al.

Journal of Neurochemistry, 2024

SLC6 Transporter Folding Diseases and Pharmacochaperoning.

Freissmuth M et al.

Handbook of Experimental Pharmacology, 2018

Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.

Bhat S et al.

The Journal of Biological Chemistry, 2017

A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.

Koban F et al.

The Journal of Biological Chemistry, 2015

The N terminus of monoamine transporters is a lever required for the action of amphetamines.

Sucic S et al.

The Journal of Biological Chemistry, 2010

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response.

Kirchheiner J et al.

Molecular Psychiatry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."