Varaico: Literature-Extracted Genetic Variants

Gene:SLC7A5
Variant:p.K204Q
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SLC7A5

NM_003486.7:p.K204Q

Associated Papers

The antiport mechanism of the human LAT1 transporter: defining the molecular determinants by means of wet and dry approaches.

Scalise M et al.

Biochemical and Biophysical Research Communications, 2025

Lysine 204 is crucial for the antiport function of the human LAT1 transporter.

Scalise M et al.

Biochimica Et Biophysica Acta. Bioenergetics, 2025

The conserved lysine residue in transmembrane helix 5 is pivotal for the cytoplasmic gating of the L-amino acid transporters.

Fort J et al.

Pnas Nexus, 2025

ATP modulates SLC7A5 (LAT1) synergistically with cholesterol.

Cosco J et al.

Scientific Reports, 2020

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