Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1A2
Variant:p.T668S
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SLCO1A2

NM_001386879.1:p.T668S

Associated Papers

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants.

Han H et al.

Drug Metabolism and Pharmacokinetics, 2022

Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants.

Araki N et al.

Drug Metabolism and Pharmacokinetics, 2022

Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

Kim B et al.

Translational and Clinical Pharmacology, 2021

34621706 (PubMed )
Supplement: tcp-29-135-s001.xls › tcp-29-135-s001

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

The SLCO1A2 -189_-188InsA polymorphism reduces clearance of rocuronium in patients submitted to elective surgeries.

Costa ACC et al.

European Journal of Clinical Pharmacology, 2017

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

Lee HH et al.

Molecular Pharmacology, 2017

Genetic polymorphisms and function of the organic anion-transporting polypeptide 1A2 and its clinical relevance in drug disposition.

Zhou Y et al.

Pharmacology, 2015

Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2.

Zhou F et al.

The Aaps Journal, 2013

Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions.

Clarke JD et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

Environmental and genetic factors affecting transport of imatinib by OATP1A2.

Eechoute K et al.

Clinical Pharmacology and Therapeutics, 2011

Pharmacogenetics of the organic anion transporting polypeptide 1A2.

Franke RM et al.

Pharmacogenomics, 2009

Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.

Badagnani I et al.

The Journal of Pharmacology and Experimental Therapeutics, 2006

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Lee W et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."