Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1A2
Variant:p.N135I
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SLCO1A2

NM_001386879.1:p.N135I

Associated Papers

The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1.

Kataoka H et al.

Journal of Pharmaceutical Sciences, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

SLC46A1 Haplotype with Predicted Functional Impact has Prognostic Value in Breast Carcinoma.

Hlavac V et al.

Molecular Diagnosis & Therapy, 2021

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

The SLCO1A2 -189_-188InsA polymorphism reduces clearance of rocuronium in patients submitted to elective surgeries.

Costa ACC et al.

European Journal of Clinical Pharmacology, 2017

Recent advance in the pharmacogenomics of human Solute Carrier Transporters (SLCs) in drug disposition.

Zhou F et al.

Advanced Drug Delivery Reviews, 2017

Genetic polymorphisms and function of the organic anion-transporting polypeptide 1A2 and its clinical relevance in drug disposition.

Zhou Y et al.

Pharmacology, 2015

Functional analysis of novel polymorphisms in the human SLCO1A2 gene that encodes the transporter OATP1A2.

Zhou F et al.

The Aaps Journal, 2013

Genetics or environment in drug transport: the case of organic anion transporting polypeptides and adverse drug reactions.

Clarke JD et al.

Expert Opinion on Drug Metabolism & Toxicology, 2012

N-Glycosylation dictates proper processing of organic anion transporting polypeptide 1B1.

Yao J et al.

Plos One, 2012

Pharmacokinetic impact of SLCO1A2 polymorphisms on imatinib disposition in patients with chronic myeloid leukemia.

Yamakawa Y et al.

Clinical Pharmacology and Therapeutics, 2011

Environmental and genetic factors affecting transport of imatinib by OATP1A2.

Eechoute K et al.

Clinical Pharmacology and Therapeutics, 2011

Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug-drug interactions, and functional consequences of polymorphisms.

König J

Handbook of Experimental Pharmacology, 2011

Interaction of methotrexate with organic-anion transporting polypeptide 1A2 and its genetic variants.

Badagnani I et al.

The Journal of Pharmacology and Experimental Therapeutics, 2006

Implications of genetic polymorphisms in drug transporters for pharmacotherapy.

Kerb R

Cancer Letters, 2006

Pharmacogenomics of human OATP transporters.

König J et al.

Naunyn-schmiedeberg's Archives of Pharmacology, 2006

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry.

Lee W et al.

The Journal of Biological Chemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."