Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1A2
Variant:p.V121I
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SLCO1A2

NM_001386879.1:p.V121I

Associated Papers

Impacts of SNPs on adverse events and trough concentration of imatinib in patients with gastrointestinal stromal tumors.

Maekawa K et al.

Drug Metabolism and Pharmacokinetics, 2022

Effects of Trough Concentration and Solute Carrier Polymorphisms on Imatinib Efficacy in Chinese Patients with Chronic Myeloid Leukemia.

Wang Q et al.

Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques, 2020

The SLCO1A2 -189_-188InsA polymorphism reduces clearance of rocuronium in patients submitted to elective surgeries.

Costa ACC et al.

European Journal of Clinical Pharmacology, 2017

Genetic polymorphisms and function of the organic anion-transporting polypeptide 1A2 and its clinical relevance in drug disposition.

Zhou Y et al.

Pharmacology, 2015

Pharmacokinetic impact of SLCO1A2 polymorphisms on imatinib disposition in patients with chronic myeloid leukemia.

Yamakawa Y et al.

Clinical Pharmacology and Therapeutics, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."