Varaico: Literature-Extracted Genetic Variants

Gene:SLCO1B1
Variant:p.G71R
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SLCO1B1

NM_006446.5:p.G71R

Associated Papers

Intrinsic Factors Influencing Simvastatin and Simvastatin Acid Pharmacokinetics: Age-Related Studies in Thai Adults and Cross-Population Comparisons.

Srimatimanon T et al.

Clinical and Translational Science, 2026

Genetic variation features of neonatal hyperbilirubinemia caused by inherited diseases.

You JY et al.

World Journal of Clinical Pediatrics, 2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction.

Zhou Y et al.

The Pharmacogenomics Journal, 2024

38802404 (PubMed )
Supplement: 41397_2024_338_MOESM1_ESM.xlsx › Sheet1

SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients.

Türkmen D et al.

International Journal of Molecular Sciences, 2024

Clinical pharmacogenetic analysis in 5,001 individuals with diagnostic Exome Sequencing data.

Lanillos J et al.

Npj Genomic Medicine, 2022

35181665 (PubMed )
Supplement: 41525_2022_283_MOESM2_ESM.xlsx › Alleles

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality.

Kiander W et al.

Pharmaceutical Research, 2021

SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function.

Zhang L et al.

Drug Metabolism and Disposition: the Biological Fate of Chemicals, 2021

Genetic variability and population diversity of the human SLCO (OATP) transporter family.

Zhang B et al.

Pharmacological Research, 2019

Combined Effects of UGT1A1 and SLCO1B1 Variants on Chinese Adult Mild Unconjugated Hyperbilirubinemia.

Bai J et al.

Frontiers in Genetics, 2019

Interindividual and interethnic variability in drug disposition: polymorphisms in organic anion transporting polypeptide 1B1 (OATP1B1; SLCO1B1).

Lee HH et al.

British Journal of Clinical Pharmacology, 2017

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition.

Ramsey LB et al.

Genome Research, 2012

[Pharmacogenomics for adverse drug reactions].

Saito Y et al.

Nihon Rinsho. Japanese Journal of Clinical Medicine, 2010

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

Saito A et al.

Journal of Human Genetics, 2009

UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients.

Onoue M et al.

International Journal of Clinical Oncology, 2009

Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer.

Bosch TM et al.

Clinical Pharmacokinetics, 2006

Risk factors for severe hyperbilirubinemia in neonates.

Huang MJ et al.

Pediatric Research, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."